How To Deliver DHEA

DHEA must be delivered to the body properly as a transdermal DHEA cream – Twist 25.

Reason 3) Medical research shows the human body metabolizes most DHEA into other hormones in the skin (the dermis). The skin is where we use most of the DHEA we make. So Twist 25 cream actually provides exactly what the body produces naturally (bioidentical DHEA) where we use it (in the skin).

(Fernand Labrie, Alain Belanger, Rene Berube, et al. University of Toronto Medical School. The Journal of Steroid Biochemistry and Molecular Biology Vol 103, Issue 2, February 2007, Pgs 178-188)

DHEA must be delivered to the body properly as a transdermal DHEA cream – Twist 25.

To know DHEA supplementation is safe think it through logically. DHEA is a naturally occurring pro-hormone. It is the most abundant pro-hormone in the body. DHEA is a base building block for hormones we produce. 50 hormones use DHEA as a precursor. The body makes DHEA and pregnenolone from cholesterol.

Why would something the body produces be harmful. No medical research studies of DHEA have shown any dangerous or harmful effects.

The goal should be to maintain levels of DHEA as when we are at our healthiest, “in our prime”. Normal levels of DHEA at age 25 are about 300 micrograms for women and 400 micrograms for men. Each pump press of Twist 25 DHEA cream provides about 20 MG DHEA. So women age 35 and up would benefit from using at least 1-2 pump presses per day; and men 2-3 pump presses per day unless otherwise directed by your physician. Testing levels regularly with a blood spot test is recommended to ensure optimum levels are maintained.

As a physician, I am not compensated in any way for sales of Twist 25 cream. Please visit my web site at

John R. Woodward, MD

Medical City Dallas